The most potent form of oestrogen before menopause, supporting bone strength, blood vessel flexibility, brain function, mood, vaginal health, and menstrual cycle regulation.

Produced by the brain to stimulate the ovaries to develop follicles and produce oestradiol; the key signal in the hormonal conversation between brain and ovaries.

Released by the brain to trigger ovulation mid-cycle and support the production of oestradiol and progesterone.

Produced after ovulation, progesterone balances oestradiol, calms the nervous system, supports sleep, stabilises mood, and regulates cycle length.

Supports libido, energy, muscle and bone strength, red blood cell production, cognitive function, and mood; produced by both the ovaries and adrenal glands.

A liver protein that binds oestrogen and testosterone in the blood; only unbound (free) hormones are available to act on tissues, so SHBG directly affects how much of your hormones are biologically active.

A calculated value using testosterone and SHBG that estimates how much testosterone is free and biologically active rather than bound and inactive.

The most sensitive early marker of thyroid function, produced by the brain to stimulate the thyroid gland; usually the first to change if thyroid activity shifts.

The main hormone produced by the thyroid gland, circulating in the blood as a store that is later converted to the active T3 in tissues throughout the body.

The most biologically active thyroid hormone, regulating energy use, body temperature, heart rhythm, and brain function; mostly produced by converting T4 in tissues rather than by the thyroid directly.

Antibodies indicating the immune system is reacting against an enzyme the thyroid uses to produce hormones; the more clinically relevant of the two thyroid antibody markers.

Antibodies indicating the immune system is reacting against a protein the thyroid uses to make hormones; less specific than Anti-TPO and best interpreted alongside your full thyroid panel.

A pituitary hormone best known for milk production but also influencing menstrual cycle regulation, breast tissue health, mood, and energy; rises naturally with stress, exercise, and certain medications.

An enzyme reflecting bone turnover (how actively bone is being broken down and rebuilt), most powerful when read alongside calcium, vitamin D, and PTH to build a complete bone health picture.

Vital for bone strength, muscle function, and nerve signalling; interpreted alongside vitamin D, PTH, and ALP, calcium helps reveal how your body is managing one of its most important minerals during hormonal change.

Partners with calcium to form the mineral structure of bones and teeth, and is essential for energy metabolism and cell function.

Regulates calcium and phosphate by mobilising calcium from bone when blood levels fall; tracking PTH alongside calcium and vitamin D shows how hard your body is working to maintain mineral balance.

A fat-soluble hormone precursor made from sunlight on skin that helps the gut absorb calcium and phosphate, supporting bone strength, muscle function, immune regulation, and mood.

The protein in red blood cells that carries oxygen from the lungs to every tissue in the body and a key marker of blood health and energy levels.

Carry haemoglobin and deliver oxygen throughout the body; the count reflects how well your body is producing and maintaining these cells.

The frontline of your immune system, fighting infections, responding to inflammation, and playing a role in allergic reactions.

Small cell fragments that help your blood clot by rushing to the site of injury; the count reflects your blood's clotting capacity.

A combined measure of all cholesterol types (both protective HDL and less desirable LDL); paired with your individual lipid markers, it gives the full cardiovascular picture.

Carries cholesterol from the liver to tissues; when elevated, excess cholesterol can accumulate in artery walls over time, making LDL the primary target for cardiovascular risk reduction.

Carries cholesterol away from the arteries back to the liver for processing; higher HDL is generally protective, while lower HDL means less cholesterol is being cleared.

Divides total cholesterol by HDL to give a more complete picture of cardiovascular context than total cholesterol alone.

A type of fat in the blood, stored after eating and released for energy between meals; more directly influenced by refined carbohydrates, sugars, and alcohol than by dietary fat.

A sensitive marker of inflammation produced by the liver; tracking CRP over time reveals patterns of chronic low-grade inflammation that are particularly relevant during hormonal change.

Reflects average blood sugar over the past two to three months by measuring glucose attached to haemoglobin.

The body's primary stress hormone, following a strong daily rhythm (highest in the morning, lowest at night) and regulating energy, blood pressure, immune function, and blood sugar.

The most abundant steroid hormone in the body, made in the adrenal glands as a precursor for oestrogen and testosterone, helping buffer the effects of cortisol.

Measures iron circulating in the blood at the moment of testing; part of the full iron panel that together reveals the complete picture of your iron status.

The protein that stores iron in cells throughout the body and the most reliable single marker of overall iron reserves; interpreted alongside CRP and your other iron markers for the fullest picture.

Measures how much capacity the blood has to carry iron; rises when iron is low as the body increases transport capacity, helping reveal early iron changes before other markers shift.

The main protein that binds and carries iron in the blood; rises when iron is low to maximise transport efficiency, adding context to your ferritin and serum iron.

The percentage of transferrin currently carrying iron, showing how loaded the transport system is; one of the earliest markers to shift when iron status is changing.

A liver protein reflecting overall nutritional status that transports hormones, vitamins, and medications through the blood.

Involved in over 300 body processes including muscle relaxation, nerve function, energy production, bone health, and blood sugar regulation; one of the most underappreciated minerals in midlife health.

Supports DNA synthesis, red blood cell formation, and mood regulation; works closely with B12, which is why both are included for a complete picture.

Supports nerve health, memory, mood, red blood cell formation, and DNA synthesis; absorption can decline with age and certain medications, making it especially important to track in midlife.

Vital for immune function, skin repair, wound healing, taste and smell, thyroid hormone metabolism, and the conversion of T4 to active T3.